Although THC isomers have diverse physiological effects, their modes of action are similar. Inflammation, pain, and immune cell function are all impacted by CB2 receptors. CB1 receptors bind to and stimulate the binding of delta-9-THC. Delta-8 might still work even though it has a decreased affinity for CB1 receptors. The effects of delta-8 are not as severe as those of delta-9. To achieve the same amount of psychoactivity as you would with delta 8 vs delta 10 THC, you might need to take more delta-8.