Given the advanced features and cost saving potential, automatic sampling systems have been widely adopted by various stakeholders in biopharmaceutical industry, to monitor data in real-time and reduce deviations associated with manual sampling.
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Roots Analysis has announced the addition of “Automatic Sampling in Biopharmaceuticals Applications and the Measurement of CQA, 2022-2035” report to its list of offerings.
The automatic sampling systems have diverse applications, including bioprocess / analyte monitoring, data management and advanced process control / feedback control, in biotechnology and pharmaceutical industries. As a result, several bioprocess equipment developers have been engaged in the development of user-friendly, controlled, and automated systems to increase the productivity and flexibility of the bioprocess. During each stage of biopharmaceutical manufacturing process, it is essential to ensure that the bioprocess variables and parameters are under control. Sampling is considered to be an important step in the bioprocess. However, there are several challenges associated with conventional, manual aseptic sampling technique, such as high risk of contamination of the sample, high labor costs, operator-to-operator deviations during sampling and sample preparation, lower sample frequency rates and no real-time availability of data. This has created a demand for systems that allow aseptic sampling and handling of samples, reduce errors, and increase reproducibility.
Key Market Insights
Currently, more than 55 automatic sampling systems are available in the market
Majority (71%) of the automatic sampling systems are capable of on-line monitoring, followed by off-line (22%) and at-line monitoring (7%). It is worth noting that around 25% of the automatic sampling systems offer multiplexer module for withdrawing the sterile samples, followed by systems containing routing module (23%) that can transfer the sample to various analyzers.
Around 45 companies are presently engaged in the manufacturing of automatic sampling systems, globally
The automatic sampling industry is dominated by the presence of mid-sized players (51-200 employees), representing more than 40% of the total automatic sampling system manufacturers. Further, about 15% firms were established post-2010. In addition, majority (54%) of the players engaged in this domain are based in Europe, followed by North America (32%).
Close to 20 automatic sample collection / preparation systems are presently available
Majority of the automatic sample collection / preparation systems (84%) are stand-alone systems. This is followed by integrated systems which capture 16% share in this domain. Further, most of these systems (nearly 40%) are being used in the pharmaceutical industry, followed by the biotechnology industry (35%).
Over 400 patents related to automatic sampling in biopharmaceutical industry have been filed / granted, since 2016
Owing to the increase in research and development efforts led by several industry and non-industry players engaged in this domain, close to 50% of patent applications have been filed post-2016. It is worth noting that 56% patents related to automatic sampling systems were filed / granted in the US alone.
Partnership activity in this field has increased at a CAGR of nearly 30%, between 2017 and 2021
Around 45% of the deals were inked in 2020 and 2021. Majority of the instances captured in the report (~40%) were product distribution agreements. Further, most of the agreements were inked with players based in North America (nearly 70%).
Over 25 global events related to automatic sampling systems were organized in the past couple of years
Majority (~80%) of the events related to automatic sampling systems, were organized virtually in order to comply with the guidelines in the ongoing COVID-19 pandemic. It is worth highlighting that the agendas of the events organized post-2020 include discussions on the potential, advancements and challenges associated with these systems in various bioprocessing operations.
North America is anticipated to capture over 50% of the global market share for automatic sampling systems, by 2035
The market will be primarily driven by sales of automatic sampling systems capable of on-line monitoring (59%). Further, systems which are used in upstream bioprocessing method are expected to occupy a larger share (60%) of the overall market (in terms of sales-based revenues), by 2035.
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Key Questions Answered
- Who are the key players engaged in the development of automatic sampling systems?
- What is the relative competitiveness of different automatic sampling system manufacturers?
- Who are the leading manufacturers involved in the automatic sample collection / preparation systems market?
- How has the intellectual property landscape of automatic sampling systems evolved over the years?
- What are the key agenda items being discussed in the various global events / conferences related to automatic sampling systems?
- Which partnership models are most commonly adopted by stakeholders engaged in the automatic sampling industry?
- How is the current and future market opportunity, likely to be distributed across key market segments?
The financial opportunity within the automatic sampling systems market has been analyzed across the following segments:
- Type of Monitoring Method
- On-line
- Off-line
- At-line
- Bioprocessing Method
- Upstream
- Downstream
- Working Volume
- Less than 10 mL
- 10-50 mL
- 51-100 mL
- More than 100 mL
- Scalability
- Lab
- Pilot
- Commercial
- Key Geographical Regions
- North America
- Europe
- Asia-Pacific and Rest of the World
The research also includes detailed profiles of the key players (listed below) engaged in the manufacturing of automatic sampling systems; each profile features an overview of the company, its financial information (if available), details on product portfolio, recent developments and an informed future outlook.
- Agilent Technologies
- Cytiva
- Mettler Toledo
- Pall Corporation
- Shimadzu
- Xylem
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