The first matchup of a three-game series involves the (13-7) traveling to take on the (8-11) on Friday evening. San Diego is currently on a three-game win streak and will look to extend that in this matchup. Meanwhile, Pittsburgh is hoping to snap its three-game losing streak. Yu Darvish (1-1, 4.43 ERA) is starting for San Diego, while Zach Thompson (0-2, 10.80 ERA) is on the hill for Pittsburgh.First pitch is set for 6:35 p.m. ET. Caesars Sportsbook lists Derek Sanderson Women Jersey San Diego as the -180 favorite (risk $180 to win $100) in the latest Padres vs. Pirates Ryan Spooner Kids Jersey odds. The over-under for total runs is set at 7.5. Before making any Pirates vs. Padres picks, The SportsLine Projection Model simulates every game 10,000 times and it is off to a sizzling start to the 2022 season. It's on a 25-11 roll on top-rated through three weeks, returning almost $1,100 for $100 players. Anyone following it has seen huge returns.Now, the model has set its sights on , and just locked in its picks and MLB predictions. . Now, here are several and betting lines for Pirates vs. Padres: Padres vs. Pirates moneyline: San Diego -180, Pittsburgh +160Padres vs. Pirates run-line: San Diego -1.5 (-105)Padres vs. Pirates over-under: 7.5 runsSD: Padres are 6-0 in their last six games Maxime Lagace Women Jersey as favoritesPIT: Under is 5-0-1 in Pirates' last six games following a lo s Featured Game | Pittsburgh Pirates vs. San Diego Padres Moneyline Spread Total PIT SD Why you should back the PadresLeft fielder Jurickson Profar is a great athlete who has good power, speed and plate discipline. Profar can spray the baseball all over the field and is leading the team in home runs (5) and RBI (15). On April 27, the 29-year-old went 1-for-3 with two runs scored and a three-run home run. Profar has a direct and compact swing. Darvish has a terrific arm and delivery with the ability to dominate on the mound. The five-time All-Star has an array of pitches and can rack up strikeouts. Darvish is 1-1 with an ERA of 4.43 with 20 strikeouts. In his last Anton Khudobin Women Jersey start, the 35-year-old threw six scorele s innings with one hit and seven strikeouts.Why you should back the PiratesThird baseman is a stellar defender with quick instincts and reads. Hayes has Jeremy Lauzon Kids Jersey a strong arm and throws the ball with velocity acro s the diamond. The 25-year-old has an aggre sive approach in the box and consistently hits for contact. Hayes is leading the team in batting average (.328), hits (20) with five RBIs. On April 26, he went 3-for-3 with two runs scored, an RBI and a double. Second baseman is a pure hitter who has solid home-run power. Chavis has a smooth swing with the ability to drive in runs. The 26-year-old currently has a batting average of .271 with two homers and eight runs batted in. In his last contest, Chavis went 1-for-4 with a double and a run scored.How to make Pirates vs. Padres picksSportsLine's model is leaning over on the run total, projecting 8.9 combined runs. It also says one side of the money line has all the value. Cam Neely Men Jersey So who wins Padres vs. Pirates? And which side has all the value? , and find out.