Diablo 4 is a game that rewards players for collecting and utilizing resources wisely. From alchemical ingredients to crafting materials, each resource plays a crucial role in the player's progression and survival in the game. Here are some of the best resources that players should prioritize collecting:

Gallowvine: Despite being a common resource, Gallowvine is essential for crafting healing potions and upgrading them to stronger variants like the Strong Healing Potion. It is also used in the creation of potions that provide additional armor.

Grave Dust: As a monster part, Grave Dust is a versatile material that is needed for upgrading healing potions and creating potions related to necromancy. It enhances the player's ability to resist undead enemies and improves their damage against them.

Biteberry: This herb is particularly valuable for alchemy, especially in the early stages of the game. It aids in the creation of healing potions and various elixirs, including those that provide resistance against cold.

Angelbreath: Angelbreath is a rarer herb found throughout Sanctuary. It is crucial for crafting powerful healing items and the strongest elixirs. Players should keep a keen eye out for this valuable resource, as it cannot be refined from other materials.

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Silver Ore: While not directly related to alchemy, Silver Ore is an important material for upgrading equipment. As players discover better gear, they will need ample amounts of Silver Ore to enhance and improve their favorite pieces.

Veiled Crystal: This rare resource is essential for upgrading rare and legendary weapons and armor. It can only be obtained by salvaging rare gear, making it a valuable commodity for improving the player's most powerful equipment.

Baleful Fragment: Another rare crafting material, Baleful Fragments are obtained by salvaging legendary weapons, offhands, and shields. These fragments are crucial for upgrading legendary weapons to increase their damage or imbuing them with additional abilities.

Forgotten Soul: Once players reach World Tier 3, Forgotten Souls become a highly sought-after resource. They are required for upgrading Sacred and Ancestral gear, which becomes available at this stage of the game. Forgotten Souls can be farmed during the Helltides event by mining Screaming Hell Veins and defeating Harbingers and Elites.

By actively collecting and managing these resources, players can enhance their alchemical abilities, upgrade their equipment, and gain a competitive edge in Diablo 4's challenging world of Sanctuary.

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