Tapentadol is an analgesic drug (sometimes referred to as an opiate). It is a potent painkiller with dual action. It attaches to certain microscopic regions (known as opioid receptors) in the spinal cord and brain and regulates the amount of the chemicalnoradrenalinein your brain. Your understanding of pain and how you respond to pain are both reduced as a result of these acts.
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Some health issues preclude the use of somedrugs, and other instances amedicationcan only be used with special caution. For the following reasons, it's crucial that yourhealthcareprovider is aware before you start taking tapentadol:

• if you are nursing a baby or pregnant.
• if you experience issues with the function of your kidneys or liver.
• if you experience any urinary incontinence or prostate issues.
• if you experience anybreathing difficulties, such as those brought on by asthma or chronic obstructive pulmonary disease (COPD).
• If your blood pressure has been diagnosed as being low.
• If you experience any thyroid or adrenal gland issues.
• ifepilepsyaffects you.
• if you experience bile duct issues.
• if you have an inflammatory gastrointestinal condition or have been constipated for longer than one week.
• if you suffer frommyasthenia gravis, which is a disease that causes muscle weakness.
• if you recently suffered a serious head injury.
• if you have ever been anillicit substanceuser.
• if you've ever experienced anadverse drug reaction.
• if you take any moremedications. This includes any prescription andover-the-counter medicationsyou are taking, in addition to herbal and alternative treatments.

• Read the printed information sheet provided by the manufacturer inside the package before you begin the therapy. In addition to providing you with a comprehensive list of potential negative consequences, it will provide you with more information abouttapentadol.
• As directed by your doctor, take tapentadol as directed. The instructions for taking it will be put on the pack's label to serve as a reminder of what your doctor advised. If required a dose of 50 mg every 4-6 hours is typically prescribed forimmediate pain treatment. Standard pills ororal liquid medicationwill be given to you. A brand of tablet calledPalexia SR(the "SR" stands for slow release as they are specially formulated to release the medication slowly to give you a more even pain relieving effect) will be provided to you if you are taking tapentadol for a long-lastingpainful condition. These tablets must be taken twice day.
• There are manystrengths of tabletsavailable, so it is a good idea to check the labels each time you gain an additional box to be sure it is the strength you are anticipating. Ask yourpharmacistfor advice if you are unsure.
• Along with a glass of water,swallow the tablet. Tapentadol may be ingested either before or after meals.Tapentadol tabletsought not to be chewed or crushed; they should be taken whole.
• Take a dose as soon as you recall if you forget to take one. If you remember when it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. To make up for the missed dose, refrain from taking two doses at once.

​It's crucial that each person who takesopioid medications, especially their loved ones and friends, be aware of the dangers of unintentional overdose and knows when to seek medical care. If you utilize other drugs that make you feel sleepy, the danger is increased. You might have taken too muchmedicationif:

• being very sleepy or queasy.
• being ill (vomiting) or feeling ill (nausea).
• breathing problems.
• awareness loss.

Rarely,drugsthat modify serotonin levels in the brain can push the levels too high and result in issues. If you are taking another drug that has this effect (such as anantidepressant), the risk is increased. If you experience any of the following, combine them, and get medical assistance:

• 'Jerky' motions or stiff muscles.
• unusually quick heartbeat.
• feverish temperature.
• being ill (vomiting, nausea), or feeling ill (nausea).
• experiencing visions or feeling delirious.

If you have any other symptoms that you believe may be related to tapentadol, consult your physician or pharmacist for more information.