Before players of Diablo Immortal are able to fully understand the concept of D2R Items Charms in the game, it's helpful to gain a bit of context about why they're in the first place. In the same way that Runes can be used to make a variety of Gems that provide new bonuses and powers to items socketed Additionally, Charms can be a method of improving one's Diablo Immortal character. They also originate from Diablo 2, where they use a similar system.
As opposed to Diablo Immortal where a Charm can be used as an item to equip and is equippable, the Diablo 2 Charm is instead kept in the inventory. Like a real-life charm which is usually kept on the personal possessions of the player, Charms in Diablo 2 only work when placed inside the inventory proper. In addition, Charms are also available in a variety of sizes and shapes, forcing players into a more efficient approach to inventory.
Similar to the Diablo 2 counterpart, Charms in Diablo Immortal are specifically used to improve a player's Skills. To further improve them, it's as simple as the use of Skill Stones on them, however there is a certain amount of luck that comes with optimizing the game's capabilities. Here are other things players need to know about Charms at the beginning before deep-diving into them:
Level Requirement: Players are granted the ability to use Charms at any time during their playthrough, but will only be available once they reach Level 56 or higher. While this is rather early in a player's diablo Immortal experience buy diablo 2 resurrected items, they're best kept to the side until players feel comfortable with the particular build they want to focus on.