Jose Berrios Jersey The reigning World Series champion will try to snap out of an extended funk when they take on the on Wednesday night at Wrigley Field in Chicago. After starting the season 13-2, the Dodgers (17-14) have lost 12 of their last 16 games. They've dropped into a tie for second place in the National League West, 1 games behind the division-leading . On Wednesday, (1-0, 3.16 ERA) will take the mound against (1-2, 4.71) and the Cubs (14-16). Los Angeles is the -160 money-line favorite (risk $160 to win $100) in Zach Duke Jersey the latest odds from William Hill Sportsbook, while the over-under for total runs scored is 7.5.That is the marquee matchup of 16 games on Wednesday's MLB schedule. Other games include the hosting the , the taking on the , and the and playing a doubleheader in St. Louis. Before making any MLB picks on those games or others in the evening, you need to .This model, which simulates every pitch of every game 10,000 Anibal Sanchez Jersey times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line . It is off to a profitable start in 2021, going 36-28 on top-rated MLB money-line picks through four weeks, returning almost $400. Anyone following it has seen huge rewards.Now, the Addison Reed Jersey model has evaluated the latest MLB lines for Wednesday and posted its best bets for the evening games. Parlaying these four MLB picks would pay over 14-1. . Top MLB picks for Wednesday, May 5One of the MLB picks the model loves for Wednesday: the model is high on Houston (+125) taking down the New York Yankees (7:05 p.m. ET). The Astros (15-14) dropped the opening game of the three-game series, 7-3, on Tuesday. The game was tied at 3-3 until a throwing error by third baseman led to a four-run sixth inning.But Houston entered the series playing good baseball; the team has won three straight series (against the , and ). Fernando Rodney Jersey In addition, the Astros were able to save all of their key bullpen arms on Tuesday night. Everyone should be available on Wednesday. Featured Game | New York Yankees vs. Houston Astros Minnesota Twins Jersey Moneyline Spread Total NYY HOU How to make MLB predictions, parlays for Wednesday, May 5The model has locked in three other MLB best bets, including one on an even bigger underdog. . So which MLB picks should you make on Wednesday for a shot at a big return of over 14-1? And which underdog do you need to be all over? , and find out.