Two division winners in the AFC will collide when the and kick off their season on Sunday at Highmark Stadium. The Bills are coming off a season in which they won their first AFC East title since 1995, while the Steelers won the Milan Lucic Jersey AFC North last season. On Sunday, the Bills are 6.5-point favorites in the from Caesars Sportsbook. The game is one of 14 on Sunday's , so which side should you back with your and NFL parlays?Other top NFL games today include two of the top contenders Jonas Gustavsson Jersey in the AFC, the and , meeting in Kansas City, and and the playing the in Jacksonville. Before making any Week 1 NFL picks or football predictions, .Hammer enters the Week 1 NFL schedule on an incredible run: Since Nov. 17, 2019, he is 50-35-5 on his NFL best bets, turning a profit of $1,170.This is the same handicapper who enjoyed 15 winning seasons in his 17-year ESPN run. In 2017, Hammer competed against 10 top handicappers in the Las Vegas Review-Journal's NFL Challenge and beat them all, finishing 50-29-6 in against-the-spread . Anyone who has followed Paul Coffey Jersey him is way up.Now, Hammer has locked in three confident best bets for Week 1. If you parlay his picks, you could be looking at a 6-1 payout. . Top Week 1 NFL expert picks Breaking down the Week Bill Ranford Jersey 1 NFL spreads, Goldberg is high on the (-8.5) covering against the . Detroit enters 2021 after three straight losing seasons, going 14-33-1. The failure prompted Lions bra s to fire coach Matt Patricia in midseason last year and replace him with first-time head coach Dan Campbell. San Francisco went 6-10 last season, finishing last in the NFC West.However, , and combined to mi s 32 games last season Grant Fuhr Jersey because of injury. They were among six significant 49ers starters last season who mi sed at least eight games due to injury. "The 49ers are healthy again, and I think they will get back to their winning ways," Goldberg told SportsLine. How to make Week 1 NFL parlays Hammer has locked in two other best bets for Jesse Puljujarvi Jersey Week 1, including one on a team he says will "wins easy," leading to a profitable cover. . What are Hammer's top Week 1 NFL expert picks? And which side cruises to any easy cover? , and find out.